› 1tuc

X-ray diffraction
2.02Å resolution

ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, CIRCULAR PERMUTANT, CUT AT S19-P20

Released:
DOI: 10.2210/pdb1tuc/pdb
PDB entry 1tuc coloured by chain, front view.
PDB entry 1tuc coloured by chain, side view.
PDB entry 1tuc coloured by chain, top view.
Source organism: Gallus gallus
Primary publication:
The order of secondary structure elements does not determine the structure of a protein but does affect its folding kinetics.
Viguera AR, Blanco FJ, Serrano L
J Mol Biol 247 670-81 (1995)
PMID: 7723022

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139741 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Spectrin alpha chain, non-erythrocytic 1 Chain: A
Molecule details ›
Chain: A
Length: 63 amino acids
Theoretical weight: 7.19 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli
UniProt:
  • Canonical: P07751 (Residues: 982-1026, 1030-1036; Coverage: 2%)
Gene names: SPTA2, SPTAN1
Sequence domains: SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P43212
Unit cell:
a: 41.8Å b: 41.8Å c: 92.04Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.214 0.214 0.29
Expression system: Escherichia coli

Quick links

Citations

10 review citations

How do small single-domain proteins fold?
Jackson SE. (1998)
9 more

13 mentions without citation

Protein reconstitution and three-dimensional domain swapping: benefits and constraints of covalency.
Carey et al. (2007)
12 more