› 1tvg

X-ray diffraction
1.6Å resolution

X-ray structure of human PP25 gene product, HSPC034. Northeast Structural Genomics Target HR1958.

Released:
DOI: 10.2210/pdb1tvg/pdb
PDB entry 1tvg coloured by chain, front view.
PDB entry 1tvg coloured by chain, side view.
PDB entry 1tvg coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Improving NMR protein structure quality by Rosetta refinement: a molecular replacement study.
Ramelot TA, Raman S, Kuzin AP, Xiao R, Ma LC, Acton TB, Hunt JF, Montelione GT, Baker D, Kennedy MA
Proteins 75 147-67 (2009)
PMID: 18816799

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195258 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Intraflagellar transport protein 25 homolog Chain: A
Molecule details ›
Chain: A
Length: 153 amino acids
Theoretical weight: 17.44 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q9Y547 (Residues: 1-144; Coverage: 99%)
Gene names: C1orf41, HSPB11, HSPC034, IFT25
Sequence domains: F5/8 type C domain
Structure domains: Galactose-binding domain-like

Ligands and Environments

2 bound ligands:
Ligand CA 1 x CA
Ligand SM 1 x SM
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: C2
Unit cell:
a: 70.974Å b: 41.617Å c: 46.779Å
α: 90° β: 102.19° γ: 90°
R-values:
R R work R free
0.215 0.215 0.244
Expression system: Not provided

Quick links

Citations

6 review citations

Practically useful: what the Rosetta protein modeling suite can do for you.
Kaufmann et al. (2010)
5 more

13 mentions without citation

A community resource of experimental data for NMR / X-ray crystal structure pairs.
Everett et al. (2016)
12 more