› 1txn

X-ray diffraction
1.7Å resolution

Crystal structure of coproporphyrinogen III oxidase

Released:
DOI: 10.2210/pdb1txn/pdb
PDB entry 1txn coloured by chain, front view.
PDB entry 1txn coloured by chain, side view.
PDB entry 1txn coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Entry authors: Kumaran D, Swaminathan S, Burley SK, New York SGX Research Center for Structural Genomics (NYSGXRC)

Function and Biology Details

Reaction catalysed: 
Coproporphyrinogen-III + O(2) + 2 H(+) = protoporphyrinogen-IX + 2 CO(2) + 2 H(2)O
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145800 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Oxygen-dependent coproporphyrinogen-III oxidase Chains: A, B
Molecule details ›
Chains: A, B
Length: 328 amino acids
Theoretical weight: 38.14 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P11353 (Residues: 1-328; Coverage: 100%)
Gene names: HEM13, YD5112.02, YDR044W
Sequence domains: Coproporphyrinogen III oxidase
Structure domains: Coproporphyrinogen III oxidase, aerobic

Ligands and Environments

1 bound ligand:
Ligand GOL 1 x GOL
1 modified residue:
Ligand MSE 16 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: P41
Unit cell:
a: 71.754Å b: 71.754Å c: 117.741Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.211 0.211 0.245
Expression system: Escherichia coli

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