› 1tyh

X-ray diffraction
2.54Å resolution

Crystal Structure of Transcriptional Activator tenA from Bacillus subtilis

Released:
DOI: 10.2210/pdb1tyh/pdb
PDB entry 1tyh coloured by chain, front view.
PDB entry 1tyh coloured by chain, side view.
PDB entry 1tyh coloured by chain, top view.
Source organism: Bacillus subtilis
Entry authors: Eswaramoorthy S, Swaminathan S, Burley SK, New York SGX Research Center for Structural Genomics (NYSGXRC)

Function and Biology Details

Reaction catalysed: 
4-amino-5-aminomethyl-2-methylpyrimidine + H(2)O = 4-amino-5-hydroxymethyl-2-methylpyrimidine + ammonia
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150337 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aminopyrimidine aminohydrolase Chains: A, B, D, E
Molecule details ›
Chains: A, B, D, E
Length: 248 amino acids
Theoretical weight: 29.09 KDa
Source organism: Bacillus subtilis
Expression system: Escherichia coli
UniProt:
  • Canonical: P25052 (Residues: 2-236; Coverage: 100%)
Gene names: BSU11650, tenA
Sequence domains: TENA/THI-4/PQQC family
Structure domains: Heme oxygenase-like

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 24 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: P41
Unit cell:
a: 58.43Å b: 58.43Å c: 297.54Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.244 0.244 0.304
Expression system: Escherichia coli

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