› 1u02

X-ray diffraction
1.92Å resolution

Crystal structure of trehalose-6-phosphate phosphatase related protein

Released:
DOI: 10.2210/pdb1u02/pdb
PDB entry 1u02 coloured by chain, front view.
PDB entry 1u02 coloured by chain, side view.
PDB entry 1u02 coloured by chain, top view.
Source organism: Thermoplasma acidophilum
Primary publication:
Crystal structure of trehalose-6-phosphate phosphatase-related protein: biochemical and biological implications.
Rao KN, Kumaran D, Seetharaman J, Bonanno JB, Burley SK, Swaminathan S
Protein Sci 15 1735-44 (2006)
PMID: 16815921

Function and Biology Details

Reaction catalysed: 
Trehalose 6-phosphate + H(2)O = trehalose + phosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190841 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Trehalose-6-phosphate phosphatase-related protein Chain: A
Molecule details ›
Chain: A
Length: 239 amino acids
Theoretical weight: 27.52 KDa
Source organism: Thermoplasma acidophilum
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9HIW7 (Residues: 2-229; Coverage: 100%)
Gene name: Ta1209
Sequence domains: Trehalose-phosphatase
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand MG 1 x MG
Ligand NA 2 x NA
Ligand GOL 2 x GOL
1 modified residue:
Ligand MSE 8 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: C2
Unit cell:
a: 117.995Å b: 45.056Å c: 53.391Å
α: 90° β: 90.65° γ: 90°
R-values:
R R work R free
0.197 0.197 0.216
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Trehalose metabolism in plants.
Lunn et al. (2014)
2 more

7 mentions without citation

Trehalose and trehalose-based polymers for environmentally benign, biocompatible and bioactive materials.
Teramoto et al. (2008)
6 more