› 1u06

X-ray diffraction
1.49Å resolution

crystal structure of chicken alpha-spectrin SH3 domain

Released:
DOI: 10.2210/pdb1u06/pdb
PDB entry 1u06 coloured by chain, front view.
PDB entry 1u06 coloured by chain, side view.
PDB entry 1u06 coloured by chain, top view.
Source organism: Gallus gallus
Primary publication:
Detection of dynamic water molecules in a microcrystalline sample of the SH3 domain of alpha-spectrin by MAS solid-state NMR.
Chevelkov V, Faelber K, Diehl A, Heinemann U, Oschkinat H, Reif B
J Biomol NMR 31 295-310 (2005)
PMID: 15928996

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139741 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Spectrin alpha chain, non-erythrocytic 1 Chain: A
Molecule details ›
Chain: A
Length: 62 amino acids
Theoretical weight: 7.23 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P07751 (Residues: 965-1025; Coverage: 3%)
Gene names: SPTA2, SPTAN1
Sequence domains: SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

1 bound ligand:
Ligand AZI 3 x AZI
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P212121
Unit cell:
a: 33.6Å b: 42.25Å c: 49.61Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.176 0.175 0.188
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Recent advances in magic angle spinning solid state NMR of membrane proteins.
Wang et al. (2014)
1 more

14 mentions without citation

The role of spectrin in cell adhesion and cell-cell contact.
Machnicka et al. (2019)
13 more