1u76

X-ray diffraction
2.6Å resolution

Crystal structure of hPCNA bound to residues 452-466 of the DNA polymerase-delta-p66 subunit

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-146060 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Proliferating cell nuclear antigen Chains: A, C, E
Molecule details ›
Chains: A, C, E
Length: 261 amino acids
Theoretical weight: 28.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P12004 (Residues: 1-261; Coverage: 100%)
Gene name: PCNA
Sequence domains:
Structure domains: Proliferating Cell Nuclear Antigen
DNA polymerase delta subunit 3 Chains: B, D, F
Molecule details ›
Chains: B, D, F
Length: 15 amino acids
Theoretical weight: 1.78 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q15054 (Residues: 452-466; Coverage: 3%)
Gene names: KIAA0039, POLD3

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P3221
Unit cell:
a: 82.48Å b: 82.48Å c: 203.8Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.24 0.24 0.278
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided