Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero hexamer (preferred)
Assembly name:
PCNA homotrimer and Flap endonuclease 1 (preferred)
PDBe Complex ID:
PDB-CPX-146047 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Proliferating cell nuclear antigen
Molecule details ›
Chain: A
Length: 261 amino acids
Theoretical weight: 28.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Length: 261 amino acids
Theoretical weight: 28.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P12004 (Residues: 1-261; Coverage: 100%)
Sequence domains:
- Proliferating cell nuclear antigen, N-terminal domain
- Proliferating cell nuclear antigen, C-terminal domain
Flap endonuclease 1
Molecule details ›
Chain: B
Length: 20 amino acids
Theoretical weight: 2.2 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 20 amino acids
Theoretical weight: 2.2 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: P39748 (Residues: 331-350; Coverage: 5%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
CHESS BEAMLINE A1
Spacegroup:
P63
Expression systems:
- Escherichia coli BL21(DE3)
- Not provided
