› 1uls

X-ray diffraction
2.4Å resolution

Crystal structure of tt0140 from Thermus thermophilus HB8

Released:
DOI: 10.2210/pdb1uls/pdb
PDB entry 1uls coloured by chain, front view.
PDB entry 1uls coloured by chain, side view.
PDB entry 1uls coloured by chain, top view.
Source organism: Thermus thermophilus
Entry authors: Hisanaga Y, Ago H, Hamada K, Sugahara M, Nodake Y, Kuramitsu S, Yokoyama S, Miyano M, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP(+) = 3-oxoacyl-[acyl-carrier-protein] + NADPH
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178077 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
3-oxoacyl-[acyl carrier protein] reductase Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 245 amino acids
Theoretical weight: 26.28 KDa
Source organism: Thermus thermophilus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5SK98 (Residues: 1-245; Coverage: 100%)
Gene name: TTHA0750
Sequence domains: Enoyl-(Acyl carrier protein) reductase
Structure domains: NAD(P)-binding Rossmann-like Domain

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 48 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL45XU
Spacegroup: P1
Unit cell:
a: 77.26Å b: 77.33Å c: 78.67Å
α: 90.12° β: 90.96° γ: 95.12°
R-values:
R R work R free
0.196 0.196 0.252
Expression system: Escherichia coli

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