› 1uus

X-ray diffraction
2.8Å resolution

Structure of an activated Dictyostelium STAT in its DNA-unbound form

Released:
DOI: 10.2210/pdb1uus/pdb
PDB entry 1uus coloured by chain, front view.
PDB entry 1uus coloured by chain, side view.
PDB entry 1uus coloured by chain, top view.
Source organism: Dictyostelium discoideum
Primary publication:
Structure of an activated Dictyostelium STAT in its DNA-unbound form.
Soler-Lopez M, Petosa C, Fukuzawa M, Ravelli R, Williams JG, Müller CW
Mol Cell 13 791-804 (2004)
PMID: 15053873

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126400 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Signal transducer and activator of transcription A Chain: A
Molecule details ›
Chain: A
Length: 473 amino acids
Theoretical weight: 53.38 KDa
Source organism: Dictyostelium discoideum
Expression system: Escherichia coli
UniProt:
  • Canonical: O00910 (Residues: 235-707; Coverage: 67%)
Gene names: DDB_G0281381, dstA, stat5, statA
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
1 modified residue:
Ligand PTR 1 x PTR

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: C2221
Unit cell:
a: 125.9Å b: 145Å c: 66.5Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.198 0.257
Expression system: Escherichia coli

Quick links

Citations

8 review citations

Comparative genomics of transcription factors and chromatin proteins in parasitic protists and other eukaryotes.
Iyer et al. (2008)
7 more

1 mention without citation

Structural basis for DNA recognition by STAT6.
Li et al. (2016)