› 1ux6

X-ray diffraction
1.9Å resolution

Structure of a thrombospondin C-terminal fragment reveals a novel calcium core in the type 3 repeats

Released:
DOI: 10.2210/pdb1ux6/pdb
PDB entry 1ux6 coloured by chain, front view.
PDB entry 1ux6 coloured by chain, side view.
PDB entry 1ux6 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of a thrombospondin C-terminal fragment reveals a novel calcium core in the type 3 repeats.
Kvansakul M, Adams JC, Hohenester E
EMBO J 23 1223-33 (2004)
PMID: 15014436

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139878 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thrombospondin-1 Chain: A
Molecule details ›
Chain: A
Length: 350 amino acids
Theoretical weight: 39.72 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P07996 (Residues: 834-1170; Coverage: 29%)
Gene names: THBS1, TSP, TSP1
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand CA 16 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.6
Spacegroup: R32
Unit cell:
a: 162.34Å b: 162.34Å c: 85.14Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.199 0.199 0.227
Expression system: Homo sapiens

Quick links

Citations

23 review citations

Roles of fascin in cell adhesion and motility.
Adams JC. (2004)
22 more

17 mentions without citation

The thrombospondins.
Adams et al. (2011)
16 more