› 1uz3

X-ray diffraction
1.1Å resolution

Crystal structure of novel protein EMSY

Released:
DOI: 10.2210/pdb1uz3/pdb
PDB entry 1uz3 coloured by chain, front view.
PDB entry 1uz3 coloured by chain, side view.
PDB entry 1uz3 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the ENT domain of human EMSY.
Chavali GB, Ekblad CM, Basu BP, Brissett NC, Veprintsev D, Hughes-Davies L, Kouzarides T, Itzhaki LS, Doherty AJ
J Mol Biol 350 964-73 (2005)
PMID: 15978617

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182277 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
BRCA2-interacting transcriptional repressor EMSY Chains: A, B
Molecule details ›
Chains: A, B
Length: 102 amino acids
Theoretical weight: 11.48 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q7Z589 (Residues: 1-100; Coverage: 8%)
Gene names: C11orf30, EMSY, GL002
Sequence domains: ENT domain
Structure domains: ENT domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX14.2
Spacegroup: P21
Unit cell:
a: 31.643Å b: 55.538Å c: 51.278Å
α: 90° β: 92.53° γ: 90°
R-values:
R R work R free
0.145 not available 0.199
Expression system: Escherichia coli

Quick links

Citations

3 review citations

The 11q13-q14 amplicon: clinicopathological correlations and potential drivers.
Wilkerson et al. (2013)
2 more

2 mentions without citation

On the Dielectric "Constant" of Proteins: Smooth Dielectric Function for Macromolecular Modeling and Its Implementation in DelPhi.
Li et al. (2013)
1 more