› 1v00

X-ray diffraction
1.7Å resolution

Erythrina cristagalli lectin

Released:
DOI: 10.2210/pdb1v00/pdb
PDB entry 1v00 coloured by chain, front view.
PDB entry 1v00 coloured by chain, side view.
PDB entry 1v00 coloured by chain, top view.
Source organism: Erythrina crista-galli
Primary publication:
Crystal structures of Erythrina cristagalli lectin with bound N-linked oligosaccharide and lactose.
Turton K, Natesh R, Thiyagarajan N, Chaddock JA, Acharya KR
Glycobiology 14 923-9 (2004)
PMID: 15201215

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180550 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Legume lectin domain-containing protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 242 amino acids
Theoretical weight: 26.57 KDa
Source organism: Erythrina crista-galli
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6YD91 (Residues: 1-242; Coverage: 100%)
Gene name: ECL
Sequence domains: Legume lectin domain
Structure domains: Jelly Rolls

Ligands and Environments

Carbohydrate polymer : NEW Components: BGC, GAL
Carbohydrate polymer
2 bound ligands:
Ligand MN 4 x MN
Ligand CA 4 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX14.1
Spacegroup: P21
Unit cell:
a: 54.9Å b: 167.23Å c: 55.13Å
α: 90° β: 97.08° γ: 90°
R-values:
R R work R free
0.172 0.172 0.195
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Bridging lectin binding sites by multivalent carbohydrates.
Wittmann et al. (2013)
21 other articles

1 mention without citation

In silico Screening and Evaluation of Plasmodium falciparum Protein Kinase 5 (PK5) Inhibitors.
Eubanks et al. (2018)