› 1v10

X-ray diffraction
1.7Å resolution

Structure of Rigidoporus lignosus laccase from hemihedrally twinned crystals

Released:
DOI: 10.2210/pdb1v10/pdb
PDB entry 1v10 coloured by chain, front view.
PDB entry 1v10 coloured by chain, side view.
PDB entry 1v10 coloured by chain, top view.
Source organism: Rigidoporus microporus
Primary publication:
The structure of Rigidoporus lignosus Laccase containing a full complement of copper ions, reveals an asymmetrical arrangement for the T3 copper pair.
Garavaglia S, Cambria MT, Miglio M, Ragusa S, Iacobazzi V, Palmieri F, D'Ambrosio C, Scaloni A, Rizzi M
J Mol Biol 342 1519-31 (2004)
PMID: 15364578

Function and Biology Details

Reaction catalysed: 
4 benzenediol + O(2) = 4 benzosemiquinone + 2 H(2)O
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179730 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Laccase Chain: A
Molecule details ›
Chain: A
Length: 521 amino acids
Theoretical weight: 55.6 KDa
Source organism: Rigidoporus microporus
UniProt:
  • Canonical: Q6H9H7 (Residues: 1-521; Coverage: 100%)
Sequence domains:
Structure domains: Cupredoxins - blue copper proteins

Ligands and Environments

1 bound ligand:
Ligand CU 4 x CU
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P65
Unit cell:
a: 124.914Å b: 124.914Å c: 95.117Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.226 not available 0.266

Quick links

Citations

14 review citations

Fungal laccases - occurrence and properties.
Baldrian P. (2006)
13 more

13 mentions without citation

Supramolecular enzyme-mimicking catalysts self-assembled from peptides.
Liu et al. (2023)
12 more