› 1vd4

Solution NMR

Solution structure of the zinc finger domain of TFIIE alpha

Released:
DOI: 10.2210/pdb1vd4/pdb
PDB entry 1vd4 coloured by chain, ensemble of 20 models, front view.
PDB entry 1vd4 coloured by chain, ensemble of 20 models, side view.
PDB entry 1vd4 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
A novel zinc finger structure in the large subunit of human general transcription factor TFIIE.
Okuda M, Tanaka A, Arai Y, Satoh M, Okamura H, Nagadoi A, Hanaoka F, Ohkuma Y, Nishimura Y
J Biol Chem 279 51395-403 (2004)
PMID: 15385556

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151350 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
General transcription factor IIE subunit 1 Chain: A
Molecule details ›
Chain: A
Length: 62 amino acids
Theoretical weight: 7.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P29083 (Residues: 113-174; Coverage: 14%)
Gene names: GTF2E1, TF2E1
Sequence domains: TFIIB zinc-binding
Structure domains: Zinc/RING finger domain, C3HC4 (zinc finger)

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry, simulated annealing
Expression system: Escherichia coli

Quick links

Citations

5 review citations

The general transcription machinery and general cofactors.
Thomas et al. (2006)
4 more

8 mentions without citation

Near-atomic resolution visualization of human transcription promoter opening.
He et al. (2016)
7 more