› 1vqt

X-ray diffraction
2Å resolution

Crystal structure of Orotidine 5'-phosphate decarboxylase (TM0332) from Thermotoga maritima at 2.00 A resolution

Released:
DOI: 10.2210/pdb1vqt/pdb
PDB entry 1vqt coloured by chain, front view.
PDB entry 1vqt coloured by chain, side view.
PDB entry 1vqt coloured by chain, top view.
Source organism: Thermotoga maritima
Entry author: Joint Center for Structural Genomics (JCSG)

Function and Biology Details

Reaction catalysed: 
Orotidine 5'-phosphate = UMP + CO(2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194511 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Orotidine 5'-phosphate decarboxylase Chain: A
Molecule details ›
Chain: A
Length: 213 amino acids
Theoretical weight: 24.31 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9WYG7 (Residues: 1-201; Coverage: 100%)
Gene names: TM_0332, pyrF
Sequence domains: Orotidine 5'-phosphate decarboxylase / HUMPS family
Structure domains: Aldolase class I

Ligands and Environments

1 bound ligand:
Ligand EDO 9 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: C2
Unit cell:
a: 70.688Å b: 85.55Å c: 48.725Å
α: 90° β: 130.2° γ: 90°
R-values:
R R work R free
0.183 0.181 0.221
Expression system: Escherichia coli

Quick links