› 1vyi

X-ray diffraction
1.5Å resolution

Structure of the c-terminal domain of the polymerase cofactor of rabies virus: insights in function and evolution.

Released:
DOI: 10.2210/pdb1vyi/pdb
PDB entry 1vyi coloured by chain, front view.
PDB entry 1vyi coloured by chain, side view.
PDB entry 1vyi coloured by chain, top view.
Source organism: Rabies virus CVS-11
Primary publication:
Structure and function of the C-terminal domain of the polymerase cofactor of rabies virus.
Mavrakis M, McCarthy AA, Roche S, Blondel D, Ruigrok RW
J Mol Biol 343 819-31 (2004)
PMID: 15476803

Function and Biology Details

Reaction catalysed: 
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149610 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphoprotein Chain: A
Molecule details ›
Chain: A
Length: 112 amino acids
Theoretical weight: 12.71 KDa
Source organism: Rabies virus CVS-11
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P22363 (Residues: 186-297; Coverage: 38%)
Gene name: P
Sequence domains: Phosphoprotein
Structure domains: Phosphoprotein, C-terminal domain

Ligands and Environments

1 bound ligand:
Ligand GOL 5 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P3121
Unit cell:
a: 44.3Å b: 44.4Å c: 106.21Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.174 0.173 0.195
Expression system: Spodoptera frugiperda

Quick links

Citations

10 review citations

A practical overview of protein disorder prediction methods.
Ferron et al. (2006)
9 more

16 mentions without citation

Macromolecular ab initio phasing enforcing secondary and tertiary structure.
Millán et al. (2015)
15 more