Function and Biology Details
Reaction catalysed:
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Structure domain:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Ubiquitin carboxyl-terminal hydrolase 15 (preferred)
PDBe Complex ID:
PDB-CPX-195233 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ubiquitin carboxyl-terminal hydrolase 15
Molecule details ›
Chain: A
Length: 141 amino acids
Theoretical weight: 16.15 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: DUSP domain
Structure domains: DUSP-like
Length: 141 amino acids
Theoretical weight: 16.15 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q9Y4E8 (Residues: 1-120; Coverage: 12%)
Sequence domains: DUSP domain
Structure domains: DUSP-like
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Refinement method:
CANDID IN CYANA AND CNS FOR WATER REFINEMENT
Expression system: Escherichia coli BL21(DE3)
