› 1w6x

X-ray diffraction
2Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172189 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neutrophil cytosol factor 4 Chains: A, B
Molecule details ›
Chains: A, B
Length: 60 amino acids
Theoretical weight: 6.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q15080 (Residues: 174-228; Coverage: 16%)
Gene names: NCF4, SH3PXD4
Sequence domains: SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NONIUS
Spacegroup: P21
Unit cell:
a: 35.16Å b: 45.16Å c: 35.06Å
α: 90° β: 111.43° γ: 90°
R-values:
R R work R free
0.248 0.248 0.25
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

12 review citations

The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology.
Bedard et al. (2007)
11 more

5 mentions without citation

Full-length p40phox structure suggests a basis for regulation mechanism of its membrane binding.
Honbou et al. (2007)
4 more