› 1wb7

X-ray diffraction
2.24Å resolution

Iron Superoxide Dismutase (Fe-SOD) From The Hyperthermophile Sulfolobus Solfataricus. Crystal Structure of the Y41F mutant.

Released:
DOI: 10.2210/pdb1wb7/pdb
PDB entry 1wb7 coloured by chain, front view.
PDB entry 1wb7 coloured by chain, side view.
PDB entry 1wb7 coloured by chain, top view.
Source organism: Saccharolobus solfataricus
Primary publication:
The role of Tyr41 and His155 in the functional properties of superoxide dismutase from the archaeon Sulfolobus solfataricus.
Gogliettino MA, Tanfani F, Sciré A, Ursby T, Adinolfi BS, Cacciamani T, De Vendittis E
Biochemistry 43 2199-208 (2004)
PMID: 14979716

Function and Biology Details

Reaction catalysed: 
2 superoxide + 2 H(+) = O(2) + H(2)O(2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160455 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Superoxide dismutase [Fe] Chains: A, B
Molecule details ›
Chains: A, B
Length: 210 amino acids
Theoretical weight: 24.13 KDa
Source organism: Saccharolobus solfataricus
Expression system: Escherichia coli
UniProt:
  • Canonical: P80857 (Residues: 2-211; Coverage: 100%)
Gene names: SSO0316, sod
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand FE 2 x FE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MAX II BEAMLINE I711
Spacegroup: C2
Unit cell:
a: 75.188Å b: 121.753Å c: 59.42Å
α: 90° β: 128.74° γ: 90°
R-values:
R R work R free
0.181 0.181 0.209
Expression system: Escherichia coli

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Citations

1 review citation

Enzymatic Antioxidant Signatures in Hyperthermophilic Archaea.
Pedone et al. (2020)
6 other articles