› 1wck

X-ray diffraction
1.36Å resolution

Crystal structure of the C-terminal domain of BclA, the major antigen of the exosporium of the Bacillus anthracis spore.

Released:
DOI: 10.2210/pdb1wck/pdb
PDB entry 1wck coloured by chain, front view.
PDB entry 1wck coloured by chain, side view.
PDB entry 1wck coloured by chain, top view.
Source organism: Bacillus anthracis
Primary publication:
The crystal structure of the Bacillus anthracis spore surface protein BclA shows remarkable similarity to mammalian proteins.
Réty S, Salamitou S, Garcia-Verdugo I, Hulmes DJ, Le Hégarat F, Chaby R, Lewit-Bentley A
J Biol Chem 280 43073-8 (2005)
PMID: 16249180

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182971 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
BclA C-terminal domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 220 amino acids
Theoretical weight: 21.4 KDa
Source organism: Bacillus anthracis
Expression system: Escherichia coli
UniProt:
  • Canonical: Q83WB0 (Residues: 235-445; Coverage: 47%)
Gene name: bclA
Sequence domains:
Structure domains: Jelly Rolls

Ligands and Environments

1 bound ligand:
Ligand CAC 1 x CAC
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: P6322
Unit cell:
a: 68.558Å b: 68.558Å c: 163.35Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.179 0.179 0.19
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Structure, assembly, and function of the spore surface layers.
Henriques et al. (2007)
6 more

4 mentions without citation

Identification and classification of bcl genes and proteins of Bacillus cereus group organisms and their application in Bacillus anthracis detection and fingerprinting.
Leski et al. (2009)
3 more