Function and Biology Details
Reactions catalysed:
(S)-3-hydroxyacyl-CoA + NAD(+) = 3-oxoacyl-CoA + NADH
(3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H(2)O
(S)-3-hydroxybutanoyl-CoA = (R)-3-hydroxybutanoyl-CoA
A (3E)-alk-3-enoyl-CoA = a (2E)-alk-2-enoyl-CoA
(1a) [acetyl-CoA C-acyltransferase]-S-acyl-L-cyteine + acetyl-CoA = 3-oxoacyl-CoA + [acetyl-CoA C-acyltransferase]-L-cyteine
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151289 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Fatty acid oxidation complex subunit alpha
Molecule details ›
Chains: A, B
Length: 715 amino acids
Theoretical weight: 77.23 KDa
Source organism: Pseudomonas fragi
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 715 amino acids
Theoretical weight: 77.23 KDa
Source organism: Pseudomonas fragi
Expression system: Escherichia coli
UniProt:
- Canonical:
P28793 (Residues: 1-715; Coverage: 100%)
Sequence domains:
- Enoyl-CoA hydratase/isomerase
- 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
- 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
3-ketoacyl-CoA thiolase
Molecule details ›
Chains: C, D
Length: 390 amino acids
Theoretical weight: 41.52 KDa
Source organism: Pseudomonas fragi
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains: Peroxisomal Thiolase; Chain A, domain 1
Length: 390 amino acids
Theoretical weight: 41.52 KDa
Source organism: Pseudomonas fragi
Expression system: Escherichia coli
UniProt:
- Canonical: P28790 (Residues: 2-391; Coverage: 100%)
Sequence domains:
Structure domains: Peroxisomal Thiolase; Chain A, domain 1
