› 1wvq

X-ray diffraction
1.45Å resolution

Structure of conserved hypothetical protein PAE2307 from Pyrobaculum aerophilum

Released:
DOI: 10.2210/pdb1wvq/pdb
PDB entry 1wvq coloured by chain, front view.
PDB entry 1wvq coloured by chain, side view.
PDB entry 1wvq coloured by chain, top view.
Source organism: Pyrobaculum aerophilum
Primary publication:
The structure of an ancient conserved domain establishes a structural basis for stable histidine phosphorylation and identifies a new family of adenosine-specific kinases.
Lott JS, Paget B, Johnston JM, Delbaere LTJ, Sigrell-Simon JA, Banfield MJ, Baker EN
J Biol Chem 281 22131-22141 (2006)
PMID: 16737961

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187413 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenosine monophosphate-protein transferase Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 167 amino acids
Theoretical weight: 18.75 KDa
Source organism: Pyrobaculum aerophilum
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8ZVF7 (Residues: 1-164; Coverage: 100%)
Gene name: PAE2307
Sequence domains: Adenosine specific kinase
Structure domains: Ta1353-like

Ligands and Environments

1 bound ligand:
Ligand PO4 1 x PO4
1 modified residue:
Ligand NEP 3 x NEP

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: I4122
Unit cell:
a: 120.036Å b: 120.036Å c: 156.468Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.207 0.207 0.22
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Structural genomics as an approach towards understanding the biology of tuberculosis.
Baker EN. (2007)
1 more

1 mention without citation

Generative power of a protein language model trained on multiple sequence alignments.
Sgarbossa et al. (2023)