› 1x2m

Solution NMR

Solution structure of the homeobox domain of mouse LAG1 longevity assurance homolog 6

Released:
DOI: 10.2210/pdb1x2m/pdb
PDB entry 1x2m coloured by chain, ensemble of 20 models, front view.
PDB entry 1x2m coloured by chain, ensemble of 20 models, side view.
PDB entry 1x2m coloured by chain, ensemble of 20 models, top view.
Source organism: Mus musculus
Entry authors: Kamatari YO, Tomizawa T, Koshiba S, Inoue M, Kigawa T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
Palmitoyl-CoA + a sphingoid base = an N-(palmitoyl)-sphingoid base + CoA
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-183932 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ceramide synthase 6 Chain: A
Molecule details ›
Chain: A
Length: 64 amino acids
Theoretical weight: 7.16 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: Q8C172 (Residues: 76-126; Coverage: 13%)
Gene names: Cers6, Lass6
Sequence domains: Homeodomain
Structure domains: Homeodomain-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided

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