› 1x2p

Solution NMR

Solution structure of the SH3 domain of the Protein arginine N-methyltransferase 2

Released:
DOI: 10.2210/pdb1x2p/pdb
PDB entry 1x2p coloured by chain, ensemble of 20 models, front view.
PDB entry 1x2p coloured by chain, ensemble of 20 models, side view.
PDB entry 1x2p coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Chikayama E, Kigawa T, Saito K, Koshiba S, Inoue M, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
(1a) S-adenosyl-L-methionine + [protein]-L-arginine = S-adenosyl-L-homocysteine + [protein]-N(omega)-methyl-L-arginine
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157300 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein arginine N-methyltransferase 2 Chain: A
Molecule details ›
Chain: A
Length: 68 amino acids
Theoretical weight: 7.24 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P55345 (Residues: 33-87; Coverage: 13%)
Gene names: HMT1, HRMT1L1, PRMT2
Sequence domains: SH3 domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, restrainted molecular dynamics
Expression system: Not provided

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