Function and Biology

Solution structures of the SH3 domain of human rho guanine exchange factor (GEF) 16

Source organism: Homo sapiens
Biochemical function: guanyl-nucleotide exchange factor activity
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00018
Domain description: SH3 domain
Occurring in:
  1. Rho guanine nucleotide exchange factor 16

InterPro InterPro annotations
IPR001452
Domain description: SH3 domain
Occurring in:
  1. Rho guanine nucleotide exchange factor 16
IPR035797
Domain description: ARHGEF16/ARHGEF26, SH3 domain
Occurring in:
  1. Rho guanine nucleotide exchange factor 16
IPR036028
Domain description: SH3-like domain superfamily
Occurring in:
  1. Rho guanine nucleotide exchange factor 16
IPR047271
Domain description: Ephexin-like
Occurring in:
  1. Rho guanine nucleotide exchange factor 16

Structure domain

CATH CATH domain
2.30.30.40
Class: Mainly Beta
Architecture: Roll
Topology: SH3 type barrels.
Homology: SH3 Domains
Occurring in:
  1. Rho guanine nucleotide exchange factor 16
The deposited structure of PDB entry 1x6b contains 1 copy of CATH domain 2.30.30.40 (SH3 type barrels.) in Rho guanine nucleotide exchange factor 16. Showing 1 copy in chain A.