› 1xa2

X-ray diffraction
1.71Å resolution

Cobalt hexammine induced tautomeric shift in Z-DNA: the structure of d(CGCGCA).d(TGCGCG) in two crystal forms

Released:
DOI: 10.2210/pdb1xa2/pdb
PDB entry 1xa2 coloured by chain, front view.
PDB entry 1xa2 coloured by chain, side view.
PDB entry 1xa2 coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Cobalt hexammine induced tautomeric shift in Z-DNA: the structure of d(CGCGCA)*d(TGCGCG) in two crystal forms.
Thiyagarajan S, Rajan SS, Gautham N
Nucleic Acids Res 32 5945-53 (2004)
PMID: 15534365

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-114798 (preferred)
Entry contents:
2 distinct DNA molecules
Macromolecules (2 distinct):
5'-D(*CP*GP*CP*GP*CP*A)-3' Chain: A
Molecule details ›
Chain: A
Length: 6 nucleotides
Theoretical weight: 1.79 KDa
Source organism: Synthetic construct
Expression system: Not provided
5'-D(*TP*GP*CP*GP*CP*G)-3' Chain: B
Molecule details ›
Chain: B
Length: 6 nucleotides
Theoretical weight: 1.83 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand NCO 1 x NCO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P212121
Unit cell:
a: 17.976Å b: 30.926Å c: 44.625Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.226 0.208 0.24
Expression system: Not provided

Quick links

Citations

2 review citations

Promotion of rare nucleobase tautomers by metal binding.
Lippert et al. (2009)
1 more

1 mention without citation

DNA conformations and their sequence preferences.
Svozil et al. (2008)