› 1xr4

X-ray diffraction
2.37Å resolution

X-ray crystal structure of putative citrate lyase alpha chain/citrate-ACP transferase [Salmonella typhimurium]

Released:
DOI: 10.2210/pdb1xr4/pdb
PDB entry 1xr4 coloured by chain, front view.
PDB entry 1xr4 coloured by chain, side view.
PDB entry 1xr4 coloured by chain, top view.
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Entry authors: Osipiuk J, Quartey P, Moy S, Collart F, Joachimiak A, Midwest Center for Structural Genomics (MCSG)

Function and Biology Details

Reactions catalysed: 
Acetyl-CoA + citrate = acetate + (3S)-citryl-CoA
Citrate = acetate + oxaloacetate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187393 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Citrate lyase alpha chain Chains: A, B
Molecule details ›
Chains: A, B
Length: 509 amino acids
Theoretical weight: 55.45 KDa
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8ZRY1 (Residues: 1-506; Coverage: 100%)
Gene names: STM0061, citF2
Sequence domains: Citrate lyase, alpha subunit (CitF)
Structure domains: Glutaconate Coenzyme A-transferase

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 24 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-BM
Spacegroup: P212121
Unit cell:
a: 58.374Å b: 116.701Å c: 189.694Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.191 0.193 0.235
Expression system: Escherichia coli BL21(DE3)

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