› 1xu8

X-ray diffraction
2.8Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153266 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serpin B5 Chains: A, B
Molecule details ›
Chains: A, B
Length: 380 amino acids
Theoretical weight: 42.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P36952 (Residues: 1-375; Coverage: 100%)
Gene names: PI5, SERPINB5
Sequence domains: Serpin (serine protease inhibitor)
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: P212121
Unit cell:
a: 53.54Å b: 100.48Å c: 136.61Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.224 0.221 0.286
Expression system: Escherichia coli BL21

Quick links

Citations

9 review citations

An overview of the serpin superfamily.
Law et al. (2006)
8 more

6 mentions without citation

G-helix of maspin mediates effects on cell migration and adhesion.
Ravenhill et al. (2010)
5 more