› 1xxb

X-ray diffraction
2.6Å resolution

C-TERMINAL DOMAIN OF ESCHERICHIA COLI ARGININE REPRESSOR/ L-ARGININE COMPLEX

Released:
DOI: 10.2210/pdb1xxb/pdb
PDB entry 1xxb coloured by chain, front view.
PDB entry 1xxb coloured by chain, side view.
PDB entry 1xxb coloured by chain, top view.
Source organism: Escherichia coli K-12
Primary publication:
Structure of the oligomerization and L-arginine binding domain of the arginine repressor of Escherichia coli.
Van Duyne GD, Ghosh G, Maas WK, Sigler PB
J Mol Biol 256 377-91 (1996)
PMID: 8594204

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-141297 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Arginine repressor Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 78 amino acids
Theoretical weight: 8.35 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
  • Canonical: P0A6D0 (Residues: 80-156; Coverage: 49%)
Gene names: JW3206, argR, b3237, xerA
Sequence domains: Arginine repressor, C-terminal domain
Structure domains: Gyrase A; domain 2

Ligands and Environments

1 bound ligand:
Ligand ARG 6 x ARG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1
Spacegroup: C2221
Unit cell:
a: 53.5Å b: 85.4Å c: 217Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.2 0.35
Expression system: Escherichia coli

Quick links

Citations

9 review citations

Timing, self-control and a sense of direction are the secrets of multicopy plasmid stability.
Summers D. (1998)
8 more

2 mentions without citation

A new coumarin compound DCH combats methicillin-resistant Staphylococcus aureus biofilm by targeting arginine repressor.
Qu et al. (2020)
1 more