› 1y0b

X-ray diffraction
1.8Å resolution

Crystal Structure of Xanthine Phosphoribosyltransferase from Bacillus subtilis.

Released:
DOI: 10.2210/pdb1y0b/pdb
PDB entry 1y0b coloured by chain, front view.
PDB entry 1y0b coloured by chain, side view.
PDB entry 1y0b coloured by chain, top view.
Source organism: Bacillus subtilis
Entry authors: Cuff ME, Wu R, Joachimiak A, Midwest Center for Structural Genomics (MCSG)

Function and Biology Details

Reaction catalysed: 
XMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154491 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Xanthine phosphoribosyltransferase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 197 amino acids
Theoretical weight: 21.48 KDa
Source organism: Bacillus subtilis
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P42085 (Residues: 1-194; Coverage: 100%)
Gene names: BSU22070, xpt
Sequence domains: Phosphoribosyl transferase domain
Structure domains: Rossmann fold

Ligands and Environments

2 bound ligands:
Ligand NA 8 x NA
Ligand G4P 4 x G4P
1 modified residue:
Ligand MSE 12 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P21
Unit cell:
a: 42.503Å b: 115.902Å c: 73.985Å
α: 90° β: 94.3° γ: 90°
R-values:
R R work R free
0.181 0.178 0.228
Expression system: Escherichia coli BL21

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