› 1y1x

X-ray diffraction
1.95Å resolution

Structural analysis of a homolog of programmed cell death 6 protein from Leishmania major Friedlin

Released:
DOI: 10.2210/pdb1y1x/pdb
PDB entry 1y1x coloured by chain, front view.
PDB entry 1y1x coloured by chain, side view.
PDB entry 1y1x coloured by chain, top view.
Source organism: Leishmania major strain Friedlin
Entry authors: Robien MA, Hol WGJ, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-175711 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
EF-hand domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 191 amino acids
Theoretical weight: 21.7 KDa
Source organism: Leishmania major strain Friedlin
Expression system: Escherichia coli
UniProt:
  • Canonical: Q4QG08 (Residues: 53-234; Coverage: 78%)
Gene name: LMJF_13_1460
Sequence domains: EF-hand domain pair
Structure domains: EF-hand

Ligands and Environments

2 bound ligands:
Ligand CA 4 x CA
Ligand SO4 3 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-3
Spacegroup: P21212
Unit cell:
a: 86.754Å b: 92.945Å c: 52.137Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.19 0.187 0.233
Expression system: Escherichia coli

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