› 1y7q

Solution NMR

Mammalian SCAN domain dimer is a domain-swapped homologue of the HIV capsid C-terminal domain

Released:
DOI: 10.2210/pdb1y7q/pdb
PDB entry 1y7q coloured by chain, ensemble of 20 models, front view.
PDB entry 1y7q coloured by chain, ensemble of 20 models, side view.
PDB entry 1y7q coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Mammalian SCAN domain dimer is a domain-swapped homolog of the HIV capsid C-terminal domain.
Ivanov D, Stone JR, Maki JL, Collins T, Wagner G
Mol Cell 17 137-43 (2005)
PMID: 15629724

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172377 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Zinc finger protein 174 Chains: A, B
Molecule details ›
Chains: A, B
Length: 98 amino acids
Theoretical weight: 11.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15697 (Residues: 37-132; Coverage: 24%)
Gene names: ZNF174, ZSCAN8
Sequence domains: SCAN domain
Structure domains: DNA breaking-rejoining enzymes

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry simulated annealing torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

14 review citations

Origins and evolution of viruses of eukaryotes: The ultimate modularity.
Koonin et al. (2015)
13 more

8 mentions without citation

Structure of the SCAN domain from the tumor suppressor protein MZF1.
Peterson et al. (2006)
7 more