› 1ydl

X-ray diffraction
2.3Å resolution

Crystal Structure of the Human TFIIH, Northeast Structural Genomics Target HR2045.

Released:
DOI: 10.2210/pdb1ydl/pdb
PDB entry 1ydl coloured by chain, front view.
PDB entry 1ydl coloured by chain, side view.
PDB entry 1ydl coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Forouhar F, Edstrom W, Xiao R, Acton TB, Montelione GT, Tong L, Hunt JF, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180618 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
General transcription factor IIH subunit 5 Chain: A
Molecule details ›
Chain: A
Length: 79 amino acids
Theoretical weight: 9.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6ZYL4 (Residues: 6-71; Coverage: 93%)
Gene names: C6orf175, GTF2H5, TTDA
Sequence domains: Transcription factor TFIIH complex subunit Tfb5
Structure domains: TFB5-like

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 3 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: P21212
Unit cell:
a: 41.412Å b: 53.922Å c: 34.818Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.239 0.236 0.297
Expression system: Escherichia coli

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