Function and Biology Details
Reaction catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- RNA polymerase Rpb1, domain 5
- RNA polymerase Rpb1, domain 1
- DNA-directed RNA polymerase, insert domain superfamily
- DNA-directed RNA polymerase, RpoA/D/Rpb3-type
- RNA polymerase, RBP11-like subunit
- DNA-directed RNA polymerase, alpha subunit
- RNA polymerase, subunit omega/Rpo6/RPB6
- RPB6/omega subunit-like superfamily
25 more domains
Structure analysis Details
Assembly composition:
hetero hexamer (preferred)
Assembly name:
DNA-directed RNA polymerase (preferred)
PDBe Complex ID:
PDB-CPX-190210 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
DNA-directed RNA polymerase subunit alpha
Molecule details ›
Chains: A, B
Length: 314 amino acids
Theoretical weight: 34.83 KDa
Source organism: Thermus aquaticus
UniProt:
Sequence domains:
Length: 314 amino acids
Theoretical weight: 34.83 KDa
Source organism: Thermus aquaticus
UniProt:
- Canonical:
Q9KWU8 (Residues: 1-314; Coverage: 100%)
Sequence domains:
- RNA polymerase Rpb3/Rpb11 dimerisation domain
- RNA polymerase Rpb3/RpoA insert domain
- Bacterial RNA polymerase, alpha chain C terminal domain
DNA-directed RNA polymerase subunit beta
Molecule details ›
Chain: C
Length: 1119 amino acids
Theoretical weight: 124.93 KDa
Source organism: Thermus aquaticus
UniProt:
Sequence domains:
Length: 1119 amino acids
Theoretical weight: 124.93 KDa
Source organism: Thermus aquaticus
UniProt:
- Canonical: Q9KWU7 (Residues: 1-1119; Coverage: 100%)
Sequence domains:
- RNA polymerase beta subunit
- RNA polymerase Rpb2, domain 2
- RNA polymerase Rpb2, domain 3
- RNA polymerase beta subunit external 1 domain
- RNA polymerase Rpb2, domain 6
- RNA polymerase Rpb2, domain 7
DNA-directed RNA polymerase subunit beta'
Molecule details ›
Chains: D, J
Length: 1524 amino acids
Theoretical weight: 171.19 KDa
Source organism: Thermus aquaticus
UniProt:
Sequence domains:
Length: 1524 amino acids
Theoretical weight: 171.19 KDa
Source organism: Thermus aquaticus
UniProt:
- Canonical: Q9KWU6 (Residues: 1-1524; Coverage: 100%)
Sequence domains:
- RNA polymerase Rpb1, domain 1
- DNA-directed RNA polymerase subunit beta', hybrid domain
- RNA polymerase Rpb1, domain 2
- RNA polymerase Rpb1, domain 3
- RNA polymerase Rpb1, domain 4
- RNA polymerase Rpb1, domain 5
DNA-directed RNA polymerase subunit omega
Molecule details ›
Chain: K
Length: 99 amino acids
Theoretical weight: 11.64 KDa
Source organism: Thermus aquaticus
UniProt:
Sequence domains: RNA polymerase Rpb6
Structure domains: Eukaryotic RPB6 RNA polymerase subunit
Length: 99 amino acids
Theoretical weight: 11.64 KDa
Source organism: Thermus aquaticus
UniProt:
- Canonical: Q9EVV4 (Residues: 1-99; Coverage: 100%)
Sequence domains: RNA polymerase Rpb6
Structure domains: Eukaryotic RPB6 RNA polymerase subunit
