Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134427 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Interleukin-2
Molecule details ›
Chain: A
Length: 133 amino acids
Theoretical weight: 15.44 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains: Interleukin 2
Structure domains: Growth Hormone; Chain: A;
Length: 133 amino acids
Theoretical weight: 15.44 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical:
P60568 (Residues: 21-153; Coverage: 100%)
Sequence domains: Interleukin 2
Structure domains: Growth Hormone; Chain: A;
Interleukin-2 receptor subunit alpha
Molecule details ›
Chain: B
Length: 219 amino acids
Theoretical weight: 24.77 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains: Sushi repeat (SCR repeat)
Structure domains:
Length: 219 amino acids
Theoretical weight: 24.77 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical: P01589 (Residues: 22-238; Coverage: 87%)
Sequence domains: Sushi repeat (SCR repeat)
Structure domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SSRL BEAMLINE BL11-1
Spacegroup:
P3221
Expression system: Trichoplusia ni
