› 1zb8

X-ray diffraction
2.4Å resolution

Crystal structure of Xylella fastidiosa organic peroxide resistance protein

Released:
DOI: 10.2210/pdb1zb8/pdb
PDB entry 1zb8 coloured by chain, front view.
PDB entry 1zb8 coloured by chain, side view.
PDB entry 1zb8 coloured by chain, top view.
Source organism: Xylella fastidiosa 9a5c
Primary publication:
Structural insights into enzyme-substrate interaction and characterization of enzymatic intermediates of organic hydroperoxide resistance protein from Xylella fastidiosa.
Oliveira MA, Guimarães BG, Cussiol JR, Medrano FJ, Gozzo FC, Netto LE
J Mol Biol 359 433-45 (2006)
PMID: 16631787

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192882 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Organic hydroperoxide resistance protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 143 amino acids
Theoretical weight: 14.96 KDa
Source organism: Xylella fastidiosa 9a5c
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9PCF4 (Residues: 1-143; Coverage: 100%)
Gene name: XF_1827
Sequence domains: OsmC-like protein
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand PE4 2 x PE4
1 modified residue:
Ligand OCS 2 x OCS

Experiments and Validation Details

Entry percentile scores
X-ray source: LNLS BEAMLINE D03B-MX1
Spacegroup: P6522
Unit cell:
a: 91.697Å b: 91.697Å c: 157.178Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.195 0.192 0.244
Expression system: Escherichia coli BL21

Quick links

Citations

3 review citations

Why do bacteria use so many enzymes to scavenge hydrogen peroxide?
Mishra et al. (2012)
2 more

4 mentions without citation

Reduction of 1-Cys peroxiredoxins by ascorbate changes the thiol-specific antioxidant paradigm, revealing another function of vitamin C.
Monteiro et al. (2007)
3 more