Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Tyrosine-protein kinase Fyn (preferred)
PDBe Complex ID:
PDB-CPX-138961 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine-protein kinase Fyn
Molecule details ›
Chain: A
Length: 59 amino acids
Theoretical weight: 6.74 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: SH3 domain
Structure domains: SH3 Domains
Length: 59 amino acids
Theoretical weight: 6.74 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P06241 (Residues: 84-142; Coverage: 11%)
Sequence domains: SH3 domain
Structure domains: SH3 Domains
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Refinement method:
Inferential Structure Determination,
Markov Chain Monte Carlo Sampling,
Replica-exchange Monte Carlo,
Gibbs sampling,
Hybrid Monte Carlo,
Torsion angle dynamics
Expression system: Escherichia coli
