› 1zbu

X-ray diffraction
3Å resolution

crystal structure of full-length 3'-exonuclease

Released:
DOI: 10.2210/pdb1zbu/pdb
PDB entry 1zbu coloured by chain, front view.
PDB entry 1zbu coloured by chain, side view.
PDB entry 1zbu coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Cheng Y, Patel DJ

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184862 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
3'-5' exoribonuclease 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 349 amino acids
Theoretical weight: 40.56 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8IV48 (Residues: 1-349; Coverage: 100%)
Gene names: 3'EXO, ERI1, THEX1
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand MG 8 x MG
Ligand AMP 4 x AMP
1 modified residue:
Ligand MSE 44 x MSE

Experiments and Validation Details

Entry percentile scores
Spacegroup: P3121
Unit cell:
a: 215.843Å b: 215.843Å c: 114.468Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.201 0.199 0.225
Expression system: Escherichia coli

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