› 1znm

Solution NMR

A zinc finger with an artificial beta-turn, original sequence taken from the third zinc finger domain of the human transcriptional repressor protein YY1 (YING and YANG 1, a delta transcription factor), nmr, 34 structures

Released:
DOI: 10.2210/pdb1znm/pdb
PDB entry 1znm coloured by chain, ensemble of 34 models, front view.
PDB entry 1znm coloured by chain, ensemble of 34 models, side view.
PDB entry 1znm coloured by chain, ensemble of 34 models, top view.
Source organism: Homo sapiens
Primary publication:
Design, synthesis and structure of a zinc finger with an artificial beta-turn.
Viles JH, Patel SU, Mitchell JB, Moody CM, Justice DE, Uppenbrink J, Doyle PM, Harris CJ, Sadler PJ, Thornton JM
J. Mol. Biol. 279 973-86 (1998)
PMID: 9642075

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150483 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcriptional repressor protein YY1 Chain: A
Molecule details ›
Chain: A
Length: 28 amino acids
Theoretical weight: 3.23 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P25490 (Residues: 352-379; Coverage: 7%)
Gene names: INO80S, YY1
Sequence domains: Zinc finger, C2H2 type

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
1 modified residue:
Ligand NVA 1 x NVA

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY, SIMULATED ANNEALING
Expression system: Not provided

Quick links

Citations

3 review citations

Protein backbone engineering as a strategy to advance foldamers toward the frontier of protein-like tertiary structure.
Reinert et al. (2014)
2 more

1 mention without citation

Native, sequential protein folding via anchored N and C protein termini.
Alberti S. (2016)