› › Structure analysis

beta PIX-SH3 complexed with an atypical peptide from alpha-PAK

Solution NMR
PDB entry 1zsg coloured by chain, ensemble of 30 models, front view.
PDB entry 1zsg coloured by chain, ensemble of 30 models, side view.
PDB entry 1zsg coloured by chain, ensemble of 30 models, top view.
Source organism: Homo sapiens
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Serine/threonine-protein kinase PAK 1 and Rho guanine nucleotide exchange factor 7
hide full assembly name
Multimeric state: hetero dimer
Accessible surface area: 6561.03 Å2
Buried surface area: 1092.29 Å2
Dissociation area: 546.14 Å2
Dissociation energy (ΔGdiss): -3.61 kcal/mol
Dissociation entropy (TΔSdiss): 8.92 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-171569

Macromolecules

Rho guanine nucleotide exchange factor 7
Chain: A
Length: 65 amino acids
Theoretical weight: 7.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q14155 (Residues: 179-243; Coverage: 8%)
Gene names: ARHGEF7, COOL1, KIAA0142, Nbla10314, P85SPR, PAK3BP, PIXB
Pfam: Variant SH3 domain
InterPro:
CATH: SH3 Domains
Rho guanine nucleotide exchange factor 7 in PDB entry 1zsg, assembly 1, front view.
Rho guanine nucleotide exchange factor 7 in PDB entry 1zsg, assembly 1, side view.
Rho guanine nucleotide exchange factor 7 in PDB entry 1zsg, assembly 1, top view.
Molecule details ›

Search similar proteins

Serine/threonine-protein kinase PAK 1
Chain: B
Length: 22 amino acids
Theoretical weight: 2.42 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q13153 (Residues: 183-204; Coverage: 4%)
Gene name: PAK1
Serine/threonine-protein kinase PAK 1 in PDB entry 1zsg, assembly 1, front view.
Serine/threonine-protein kinase PAK 1 in PDB entry 1zsg, assembly 1, side view.
Serine/threonine-protein kinase PAK 1 in PDB entry 1zsg, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links