Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Complement C3b complex (preferred)
PDBe Complex ID:
PDB-CPX-133822 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (4 distinct):
Complement C3 beta chain
Molecule details ›
Chain: A
Length: 643 amino acids
Theoretical weight: 71.27 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains:
Length: 643 amino acids
Theoretical weight: 71.27 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P01024 (Residues: 23-665; Coverage: 39%)
Sequence domains:
- Macroglobulin domain MG1
- MG2 domain
- Macroglobulin domain MG3
- Macroglobulin domain MG4
- Alpha-2-macroglobulin bait region domain
Complement C3 alpha chain
Molecule details ›
Chain: B
Length: 991 amino acids
Theoretical weight: 113.08 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains:
Length: 991 amino acids
Theoretical weight: 113.08 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P01024 (Residues: 673-1663; Coverage: 60%)
Sequence domains:
- Anaphylotoxin-like domain
- Alpha-2-macroglobulin family
- Complement component 3, CUB domain 1
- A-macroglobulin TED domain
- Complement component 3, CUB domain 2
- A-macroglobulin receptor binding domain
- UNC-6/NTR/C345C module
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE ID14-4
Spacegroup:
I222
