› 2azs

Solution NMR

NMR structure of the N-terminal SH3 domain of Drk (calculated without NOE restraints)

Released:
DOI: 10.2210/pdb2azs/pdb
PDB entry 2azs coloured by chain, ensemble of 10 models, front view.
PDB entry 2azs coloured by chain, ensemble of 10 models, side view.
PDB entry 2azs coloured by chain, ensemble of 10 models, top view.
Source organism: Drosophila melanogaster
Primary publication:
Structural comparison of the unstable drkN SH3 domain and a stable mutant.
Bezsonova I, Singer A, Choy WY, Tollinger M, Forman-Kay JD
Biochemistry 44 15550-60 (2005)
PMID: 16300404

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170587 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Growth factor receptor-bound protein 2 Chain: A
Molecule details ›
Chain: A
Length: 59 amino acids
Theoretical weight: 6.87 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli
UniProt:
  • Canonical: Q08012 (Residues: 1-59; Coverage: 28%)
Gene names: CG6033, E(sev)2B, Grb2, drk
Sequence domains: SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Pathological unfoldomics of uncontrolled chaos: intrinsically disordered proteins and human diseases.
Uversky et al. (2014)
1 more

2 mentions without citation

ProBiS-CHARMMing: Web Interface for Prediction and Optimization of Ligands in Protein Binding Sites.
Konc et al. (2015)
1 more