› 2b05

X-ray diffraction
2.55Å resolution

Crystal Structure of 14-3-3 gamma in complex with a phosphoserine peptide

Released:
DOI: 10.2210/pdb2b05/pdb
PDB entry 2b05 coloured by chain, front view.
PDB entry 2b05 coloured by chain, side view.
PDB entry 2b05 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Papagrigoriou E, Elkins J, Arrowsmith C, Zhao Y, Debreczeni EJ, Edwards A, Weigelt J, Doyle D, von Delft F, Turnbull A, Yang X

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
hetero tetramer (preferred)
hetero 24-mer
Assembly name:
PDBe Complex ID:
PDB-CPX-158520 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
14-3-3 protein gamma Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 246 amino acids
Theoretical weight: 28.21 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61981 (Residues: 2-247; Coverage: 100%)
Gene name: YWHAG
Sequence domains: 14-3-3 protein
Structure domains: 14-3-3 domain
peptide Chains: G, H, I, J, K, L
Molecule details ›
Chains: G, H, I, J, K, L
Length: 6 amino acids
Theoretical weight: 737 Da
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:
Ligand SEP 6 x SEP

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P41212
Unit cell:
a: 121.571Å b: 121.571Å c: 313.164Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.266 0.258 0.302
Expression systems:
  • Escherichia coli
  • Not provided

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