› 2b0y

Solution NMR

Solution Structure of a peptide mimetic of the fourth cytoplasmic loop of the G-protein coupled CB1 cannabinoid receptor

Released:
DOI: 10.2210/pdb2b0y/pdb
PDB entry 2b0y coloured by chain, ensemble of 20 models, front view.
PDB entry 2b0y coloured by chain, ensemble of 20 models, side view.
PDB entry 2b0y coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Unique helical conformation of the fourth cytoplasmic loop of the CB1 cannabinoid receptor in a negatively charged environment.
Grace CR, Cowsik SM, Shim JY, Welsh WJ, Howlett AC
J Struct Biol 159 359-68 (2007)
PMID: 17524664

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149293 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cannabinoid receptor 1 Chain: A
Molecule details ›
Chain: A
Length: 17 amino acids
Theoretical weight: 2.06 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P21554 (Residues: 400-416; Coverage: 4%)
Gene names: CNR, CNR1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry and simulated annealing(DYANA)
Expression system: Not provided

Quick links

Citations

2 review citations

CB(1) cannabinoid receptors and their associated proteins.
Howlett et al. (2010)
1 more

2 mentions without citation

Unique helical conformation of the fourth cytoplasmic loop of the CB1 cannabinoid receptor in a negatively charged environment.
Grace et al. (2007)
1 more