› 2b5m

X-ray diffraction
2.92Å resolution

Crystal Structure of DDB1

Released:
DOI: 10.2210/pdb2b5m/pdb
PDB entry 2b5m coloured by chain, front view.
PDB entry 2b5m coloured by chain, side view.
PDB entry 2b5m coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of DDB1 in complex with a paramyxovirus V protein: viral hijack of a propeller cluster in ubiquitin ligase.
Li T, Chen X, Garbutt KC, Zhou P, Zheng N
Cell 124 105-17 (2006)
PMID: 16413485

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172469 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA damage-binding protein 1 Chain: A
Molecule details ›
Chain: A
Length: 1140 amino acids
Theoretical weight: 127.12 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q16531 (Residues: 1-1140; Coverage: 100%)
Gene names: DDB1, XAP1
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2, ALS BEAMLINE 8.2.1
Spacegroup: P212121
Unit cell:
a: 63.38Å b: 133.834Å c: 184.715Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.235 0.232 0.277
Expression system: Spodoptera frugiperda

Quick links

Citations

50 review citations

WD40 proteins propel cellular networks.
Stirnimann et al. (2010)
49 more

5 mentions without citation

Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex.
Scrima et al. (2008)
4 more