› 2b9r

X-ray diffraction
2.9Å resolution

Crystal Structure of Human Cyclin B1

Released:
DOI: 10.2210/pdb2b9r/pdb
PDB entry 2b9r coloured by chain, front view.
PDB entry 2b9r coloured by chain, side view.
PDB entry 2b9r coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The crystal structure of human cyclin B.
Petri ET, Errico A, Escobedo L, Hunt T, Basavappa R
Cell Cycle 6 1342-9 (2007)
PMID: 17495533

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146988 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
G2/mitotic-specific cyclin-B1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 269 amino acids
Theoretical weight: 30.84 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P14635 (Residues: 165-433; Coverage: 62%)
Gene names: CCNB, CCNB1
Sequence domains:
Structure domains: Cyclin-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P6222
Unit cell:
a: 117.169Å b: 117.169Å c: 197.685Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.249 0.243 0.308
Expression system: Escherichia coli

Quick links

Citations

8 review citations

Cyclin-dependent kinases and cell-cycle transitions: does one fit all?
Hochegger et al. (2008)
7 more

17 mentions without citation

Ser or Leu: structural snapshots of mistranslation in Candida albicans.
Sárkány et al. (2014)
16 more