Function and Biology Details
Reaction catalysed:
Selective cleavage of Arg-|-Thr and then Arg-|-Ile bonds in prothrombin to form thrombin.
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
Structure domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Coagulation factor Xa complex (preferred)
PDBe Complex ID:
PDB-CPX-133209 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Factor X light chain
Molecule details ›
Chain: A
Length: 52 amino acids
Theoretical weight: 5.62 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Coagulation Factor Xa inhibitory site
Structure domains: Laminin
Length: 52 amino acids
Theoretical weight: 5.62 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P00742 (Residues: 126-177; Coverage: 11%)
Sequence domains: Coagulation Factor Xa inhibitory site
Structure domains: Laminin
Activated factor Xa heavy chain
Molecule details ›
Chain: B
Length: 249 amino acids
Theoretical weight: 28.22 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases
Length: 249 amino acids
Theoretical weight: 28.22 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P00742 (Residues: 220-468; Coverage: 55%)
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases
