› 2cg7

X-ray diffraction
1.2Å resolution

SECOND AND THIRD FIBRONECTIN TYPE I MODULE PAIR (CRYSTAL FORM II).

Released:
DOI: 10.2210/pdb2cg7/pdb
PDB entry 2cg7 coloured by chain, front view.
PDB entry 2cg7 coloured by chain, side view.
PDB entry 2cg7 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The solution and crystal structures of a module pair from the Staphylococcus aureus-binding site of human fibronectin--a tale with a twist.
Rudiño-Piñera E, Ravelli RB, Sheldrick GM, Nanao MH, Korostelev VV, Werner JM, Schwarz-Linek U, Potts JR, Garman EF
J Mol Biol 368 833-44 (2007)
PMID: 17368672

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136132 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fibronectin Chain: A
Molecule details ›
Chain: A
Length: 90 amino acids
Theoretical weight: 10.12 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P02751 (Residues: 93-182; Coverage: 4%)
Gene names: FN, FN1
Sequence domains: Fibronectin type I domain
Structure domains: Complement Module, domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P21212
Unit cell:
a: 52.651Å b: 29.419Å c: 51.009Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.19 0.189 0.219
Expression system: Komagataella pastoris

Quick links

Citations

4 review citations

Fibronectin: a multidomain host adhesin targeted by bacterial fibronectin-binding proteins.
Henderson et al. (2011)
3 more

14 mentions without citation

Crystal structures of fibronectin-binding sites from Staphylococcus aureus FnBPA in complex with fibronectin domains.
Bingham et al. (2008)
13 more