› 2coo

Solution NMR

Solution structure of the e3_binding domain of dihydrolipoamide branched chaintransacylase

Released:
DOI: 10.2210/pdb2coo/pdb
PDB entry 2coo coloured by chain, ensemble of 20 models, front view.
PDB entry 2coo coloured by chain, ensemble of 20 models, side view.
PDB entry 2coo coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Zhang HP, Hayashi F, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
2-methylpropanoyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine = CoA + enzyme N(6)-(S-(2-methylpropanoyl)dihydrolipoyl)lysine
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145696 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 70 amino acids
Theoretical weight: 7.31 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P11182 (Residues: 162-220; Coverage: 12%)
Gene names: BCATE2, BCKDHE2, DBT
Sequence domains: e3 binding domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided

Quick links